Diseases and Conditions That Cause Bone Loss

by Diane, M.P.H, M.S.

Many diseases and conditions can cause bone loss and osteoporosis. If you have any of the following conditions, ask your healthcare provider if you should improve your diet and lifestyle habits and/or have a bone density test:

  • AIDS/HIV
  • Ankylosing spondylitis
  • Blood and bone marrow disorders
  • Breast cancer
  • Chronic obstructive pulmonary disease (COPD), including emphysema
  • Cushing’s syndrome
  • Depression
  • Diabetes
  • Eating disorders, especially anorexia nervosa
  • Female athlete triad (includes loss of menstrual periods, an eating disorder, and excessive exercise)
  • Gastrectomy
  • Gastrointestinal bypass procedures
  • Hyperparathyroidism
  • Hyperthyroidism
  • Inflammatory bowel disease, including Crohn’s and ulcerative colitis
  • Kidney disease that is chronic and long lasting
  • Liver disease that is severe, including biliary cirrhosis
  • Lupus
  • Lymphoma and leukemia
  • Malabsorption syndromes, including celiac disease
  • Multiple myeloma
  • Multiple sclerosis
  • Organ transplants
  • Parkinson’s disease
  • Polio and post-polio syndrome
  • Poor diet, including malnutrition
  • Premature menopause
  • Prostate cancer
  • Rheumatoid arthritis
  • Scoliosis
  • Spinal cord injuries
  • Stroke
  • Thalassemia
  • Thyrotoxicosis
  • Weight loss

Note: This list may not include all diseases and conditions that may cause bone loss.

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